This class aims to teach the basic principles of MRI.
Fundamentals of MRI including signal-to-noise ratio, resolution, and contrast as dictated by physics, pulse sequences, and instrumentation. Image reconstruction via 2D FFT methods. Fast imaging reconstruction via convolution-back projection and gridding methods and FFTs. Hardware for modern MRI scanners including main field, gradient fields, RF coils, and shim supplies. Software for MRI including imaging methods such as 2D FT, RARE, SSFP, spiral and echo planar imaging methods. Fundamental tradeoffs of tailoring hardware and pulse sequences to specific applications. The modern MRI toolbox will be introduced, including selecting a slice or volume, fast imaging methods to avoid image artifacts due to physiologic motion, and methods for functional imaging. The fundamentals of MRI image artifacts (motion, magnetic susceptibility variations, RF field variations) will also be covered. The last part of the class will present emerging research opportunities and concomitant engineering research challenges including high-field MRI, hyperpolarization methods, small animal MRI, cardiac MRI, stem-cell tracking, functional MRI, parallel imaging and compressed-sensing MRI.
Tue 3:30-4:30 Cory 506
Thu 2:00-3:00 Cory 506
GSI office hours: TBD
Class Time and Location
521 Cory Hall
We are going to use Piazza for discussion and announcements. The link is here.
Bernstein, King and Zhou, Handbook of MRI Pulse Sequences Elsevier/Wiley, 2004
You can get it from Amazon here. This is an excellent book, which anyone working in MRI will want to have.
Z.-P. Liang, P. Lauterbur, Principles of Magnetic Resonance Imaging: A Signal Processing Perspective, IEEE Press. A link to Amazon Here
Haacke, Brown, Thompson, and Venkatesan, Magnetic Resonance Imaging: Physical Principles and Sequence Design, John Wiley & Sons New York, NY 1999. ISBN: 0-471-35128-8.
Richard B. Buxton, An Introduction to Functional Magnetic Resonance Imaging: Principles and Techniques, ISBN: 0521581133. Publisher: Cambridge University Press.
A list of the topics that will be covered is given here, in the order that they will be covered. This may change based on class interest, and time.
Weekly assignments consisting of problem sets and potentially some matlab programming. (20%)
Two minterms (yes min, not mid), one in the middle (30%) and one at the end (30%) of the semester.
Final project (20%)
No late hw, makeup midterms etc. without prior concent from the instructor.
We will use a paperless submission system. Please submit your homework using the DROPBOX in BSPACE in PDF format. I strongly recommend using Latex for formatting, but you can use anything you wish. A Latex template can be downloded from here. The document should include your answers to the questions, matlab code and plots as required.
Please use the standard file name which is: Firstname_Lastname_hwxx_sol.pdf. for example: Miki_Lustig_hw01_sol.pdf.
Research Topics for the project can be downloaded from Here
Lecture 01+02 Notes,
Lecture 03 Notes
Lecture 04 Notes
Lecture 06 Notes
Lecture 07 Notes
A beatiful paper on Magnetic Susceptibility by Schenck.
Lecture 08 Notes
Lecture 09 Notes
Notes for Lab I Notes
Lecture 10 Notes
Lecture 11 Notes
Lecture 12 Notes
Lecture 13 Notes
Lecture 15 Notes
Lecture 16 Notes
Lecture 17 Notes
Lecture 18 Notes
Lecture 19 Notes
Lecture 20 Notes
Lecture 21 Notes
Notes for Lab II Notes
Homework 4 can be downloaded from Here.
The Matlab question uses a Bloch simulator that was written by Brian Hargreaves. You will need bloch.c, bloch.m for the simulator. For visualization you will need: rotatePoints.m, arrow3D.m, visualizeMagn.m. These were downloaded from MatlabCentral
Here are compiled mex files: Linux 64bit, Mac OSX Intel and Windows Vista
Solutions can be downloaded from Here.