EE225E / BIOE265: Principles of Magnetic Resonance Imaging

2DFT sequence

Spring, 2016

Course Description

This class aims to teach the basic principles of MRI.
Fundamentals of MRI including signal-to-noise ratio, resolution, and contrast as dictated by physics, pulse sequences, and instrumentation. Image reconstruction via 2D FFT methods. Fast imaging reconstruction via convolution-back projection and gridding methods and FFTs. Hardware for modern MRI scanners including main field, gradient fields, RF coils, and shim supplies. Software for MRI including imaging methods such as 2D FT, RARE, SSFP, spiral and echo planar imaging methods. Fundamental tradeoffs of tailoring hardware and pulse sequences to specific applications. The modern MRI toolbox will be introduced, including selecting a slice or volume, fast imaging methods to avoid image artifacts due to physiologic motion, and methods for functional imaging. The fundamentals of MRI image artifacts (motion, magnetic susceptibility variations, RF field variations) will also be covered. The last part of the class will present emerging research opportunities and concomitant engineering research challenges including high-field MRI, hyperpolarization methods, small animal MRI, cardiac MRI, stem-cell tracking, functional MRI, parallel imaging and compressed-sensing MRI.


Office Hours


Class Time and Location

Lab Sessions:

We are going to use Piazza for discussion and announcements. The link is TBD.

Required Text

D. Nishimura Principles of Magnetic Resonance Imaging 2010
You can get in paperback(35$) and hardcover(45$) from

Optional References
  • Bernstein, King and Zhou, Handbook of MRI Pulse Sequences Elsevier/Wiley, 2004
    You can get it from Amazon here. This is an excellent book, which anyone working in MRI will want to have.

  • Z.-P. Liang, P. Lauterbur, Principles of Magnetic Resonance Imaging: A Signal Processing Perspective, IEEE Press. A link to Amazon Here

  • Haacke, Brown, Thompson, and Venkatesan, Magnetic Resonance Imaging: Physical Principles and Sequence Design, John Wiley & Sons New York, NY 1999. ISBN: 0-471-35128-8.

  • Richard B. Buxton, An Introduction to Functional Magnetic Resonance Imaging: Principles and Techniques, ISBN: 0521581133. Publisher: Cambridge University Press.

Grading (subject to adjustment):

Midterm dates:

Homework Instruction



Lecture Notes